Renal Impairment in decompensated Heart Failure
Researcher 1 Professor Mark Richards
Researcher Institution Christchurch School of Medicine & Health Sciences
Researcher 2: Dr Suetonia Palmer
Researcher 3: Professor Zoltan Endre
Researcher 4: Assoc Professor Tim Yandle
3 year Project
Amount Funded: $66,876.00
Photo: Prof Mark Richards and Assoc Prof Tim Yandle
Specific Objective(s)/Aims for this research.
The proposed study has 2 primary aims:
To conduct the first prospective systematic documentation of the prevalence, incidence, severity, nature and evolution of renal function over 12 months in an unselected cohort of patients hospitalised with decompensated (severe)heart failure;
To determine the diagnostic utility and predictive value of plasma (NGAL, cystatin C) and urinary (cystatin C, ALP, GGT, NGAL, KIM-1, IL-18 and AQP 1, 2) biomarkers of kidney injury in decompensated heart failure compared with standard tests of kidney function (plasma creatinine) and concurrent cardiac function (echocardiography and neurohormonal profile).
